Abnormal cytology after Ketoconazole in dogs

The FDA has received 51 reports of abnormal cytology in dogs after Ketoconazole. That is 2.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

51Reports
71%Marked serious
5.9%Recovered
5.9%Died or euthanised
26 daysTypical onset
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How soon it started

Same day
3 7.7%
1–2 days
3 7.7%
3–7 days
2 5.1%
1–4 weeks
13 33%
Over a month
18 46%

How the animals did

Recovered
3 5.9%
Still unwell when reported
28 55%
Died
2 3.9%
Euthanised
1 2.0%
Not known
17 33%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
8
4–7 years
14
8–11 years
12
12+ years
10

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause abnormal cytology in dogs?
51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 26 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal cytology with similar medicines

All reported side effects of Ketoconazole in dogs · Medicines most reported with abnormal cytology