Crust after Ketoconazole in dogs

The FDA has received 45 reports of crust in dogs after Ketoconazole. That is 2.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

45Reports

69%Marked serious

16%Recovered

4.4%Died or euthanised

19 daysTypical onset

How soon it started

Same day

3 8.1%

1–2 days

4 11%

3–7 days

3 8.1%

1–4 weeks

12 32%

Over a month

15 41%

How the animals did

Recovered

5 11%

Recovered with lasting effects

2 4.4%

Still unwell when reported

26 58%

Died

2 4.4%

Not known

10 22%

Problems reported at the same time

22 49%

20 44%

17 38%

15 33%

Skin rash or irritation

14 31%

Abnormal cytology

13 29%

Didn't work as expected

12 27%

Loss of appetite

11 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause crust in dogs?: 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 19 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Crust with similar medicines

Crust after Melarsomine (Immiticide) 30 reports · 0.1% of its reports
Crust after Diphenhydramine 49 reports · 1.0% of its reports
Crust after Cefpodoxime 88 reports · 2.2% of its reports
Crust after Tramadol 23 reports · 0.6% of its reports
Crust after Florfenicol + Mometasone + Terbinafine 67 reports · 1.9% of its reports
Crust after Cephalexin 33 reports · 1.2% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with crust