Abnormal radiograph finding after Isoflurane in dogs

The FDA has received 96 reports of abnormal radiograph finding in dogs after Isoflurane. That is 3.5% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

96Reports

82%Marked serious

16%Recovered

36%Died or euthanised

3 daysTypical onset

How soon it started

Same day

25 32%

1–2 days

14 18%

3–7 days

16 20%

1–4 weeks

14 18%

Over a month

10 13%

How the animals did

Recovered

13 14%

Recovered with lasting effects

2 2.1%

Still unwell when reported

23 24%

Died

21 22%

Euthanised

14 15%

Not known

23 24%

Problems reported at the same time

51 53%

48 50%

43 45%

34 35%

34 35%

31 32%

29 30%

24 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause abnormal radiograph finding in dogs?: 96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal radiograph finding with similar medicines

Abnormal radiograph finding after Melarsomine (Immiticide) 344 reports · 1.5% of its reports
Abnormal radiograph finding after Polysulfated Glycosaminoglycan 155 reports · 2.8% of its reports
Abnormal radiograph finding after Diphenhydramine 149 reports · 3.2% of its reports
Abnormal radiograph finding after Butorphanol 138 reports · 3.1% of its reports
Abnormal radiograph finding after Cefpodoxime 120 reports · 3.0% of its reports
Abnormal radiograph finding after Tramadol 201 reports · 5.3% of its reports
Abnormal radiograph finding after Florfenicol + Mometasone + Terbinafine 31 reports · 0.9% of its reports
Abnormal radiograph finding after Desoxycorticosterone Pivalate 49 reports · 1.5% of its reports
Abnormal radiograph finding after Propofol 75 reports · 2.4% of its reports
Abnormal radiograph finding after Dirlotapide 28 reports · 1.0% of its reports

All reported side effects of Isoflurane in dogs · Medicines most reported with abnormal radiograph finding