Imidacloprid + Permethrin side effects in dogs

468 reports sent to the FDA between 2009 and 2026 involve Imidacloprid + Permethrin in dogs. The most reported problems were vomiting, lethargy, itching. 23% were marked serious.

468Reports
23%Marked serious
0.0%Only medicine involved
38%Recovered
4.9%Died or euthanised
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About this medicine

Imidacloprid kills fleas (spot-on or collar).

Most reported side effects

139 30%
87 19%
49 10%
34 7.3%
25 5.3%
Tremors
17 3.6%
Breathing problems
17 3.6%
Vocalising
13 2.8%
Skin rash or irritation
13 2.8%
Drooling
13 2.8%
Fever
12 2.6%
Kidney problems
12 2.6%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

How soon problems started

Same day
62 20%
1–2 days
30 9.7%
3–7 days
19 6.1%
1–4 weeks
53 17%
Over a month
146 47%

Time from the first dose to the first sign, where both dates were reported (310 reports).

How the animals did

Recovered
169 36%
Recovered with lasting effects
11 2.4%
Still unwell when reported
88 19%
Died
14 3.0%
Euthanised
9 1.9%
Not known
177 38%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other flea and tick treatments for dogs