Sleepiness - systemic disorder after Ilunocitinib (Zenrelia) in dogs

20 reports to the FDA describe sleepiness - systemic disorder in dogs given Ilunocitinib. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports

5.0%Marked serious

40%Recovered

0.0%Died or euthanised

67 daysTypical onset

How soon it started

Same day

3 15%

1–2 days

3 15%

3–7 days

1 5.0%

1–4 weeks

2 10%

Over a month

11 55%

How the animals did

Recovered

8 40%

Still unwell when reported

8 40%

Not known

4 20%

Problems reported at the same time

10 50%

5 25%

3 15%

2 10%

2 10%

2 10%

Faecal incontinence

2 10%

Polyphagia

2 10%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Ilunocitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Zenrelia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Ilunocitinib cause sleepiness - systemic disorder in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 67 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Sleepiness - systemic disorder with similar medicines

Sleepiness - systemic disorder after Oclacitinib (Apoquel) 74 reports · 0.3% of its reports

All reported side effects of Ilunocitinib in dogs · Medicines most reported with sleepiness - systemic disorder