Tremors after Ilunocitinib (Zenrelia) in dogs

59 reports to the FDA describe tremors in dogs given Ilunocitinib. That is 2.7% of all reports for this medicine, compared with 3.4% across reports for all dog medicines.

59Reports

49%Marked serious

46%Recovered

14%Died or euthanised

22 daysTypical onset

How soon it started

Same day

6 12%

1–2 days

5 9.6%

3–7 days

6 12%

1–4 weeks

15 29%

Over a month

20 38%

How the animals did

Recovered

27 46%

Still unwell when reported

12 20%

Died

5 8.5%

Euthanised

3 5.1%

Not known

12 20%

Problems reported at the same time

22 37%

16 27%

14 24%

12 20%

9 15%

9 15%

9 15%

9 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Ilunocitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Zenrelia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Ilunocitinib cause tremors in dogs?: 59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 22 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

Tremors after Oclacitinib (Apoquel) 816 reports · 2.8% of its reports
Tremors after Cyclosporine (Atopica) 657 reports · 4.3% of its reports

All reported side effects of Ilunocitinib in dogs · Medicines most reported with tremors