Pale mucous membrane after Ilunocitinib (Zenrelia) in dogs

32 reports to the FDA describe pale mucous membrane in dogs given Ilunocitinib. That is 1.5% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

32Reports
81%Marked serious
19%Recovered
50%Died or euthanised
79 daysTypical onset
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How soon it started

Same day
1 3.8%
1–2 days
1 3.8%
3–7 days
0 0.0%
1–4 weeks
3 12%
Over a month
21 81%

How the animals did

Recovered
6 19%
Still unwell when reported
6 19%
Died
2 6.3%
Euthanised
14 44%
Not known
4 13%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
5
4–7 years
15
8–11 years
6
12+ years
4

About this medicine

Ilunocitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Zenrelia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Ilunocitinib cause pale mucous membrane in dogs?
32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 79 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pale mucous membrane with similar medicines

All reported side effects of Ilunocitinib in dogs · Medicines most reported with pale mucous membrane