Unable to walk after Grapiprant (Galliprant) in dogs

The FDA has received 107 reports of unable to walk in dogs after Grapiprant. That is 1.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

107Reports
73%Marked serious
19%Recovered
35%Died or euthanised
20 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
17 19%
1–2 days
8 9.1%
3–7 days
7 8.0%
1–4 weeks
15 17%
Over a month
41 47%

How the animals did

Recovered
20 19%
Still unwell when reported
40 37%
Died
5 4.7%
Euthanised
32 30%
Not known
10 9.3%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
0
4–7 years
7
8–11 years
26
12+ years
73

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause unable to walk in dogs?
107 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 20 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unable to walk with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with unable to walk