Not drinking after Grapiprant (Galliprant) in dogs

The FDA has received 98 reports of not drinking in dogs after Grapiprant. That is 1.1% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

98Reports

61%Marked serious

16%Recovered

26%Died or euthanised

5 daysTypical onset

How soon it started

Same day

10 12%

1–2 days

20 25%

3–7 days

16 20%

1–4 weeks

13 16%

Over a month

22 27%

How the animals did

Recovered

16 16%

Still unwell when reported

39 40%

Died

5 5.1%

Euthanised

20 20%

Not known

18 18%

Problems reported at the same time

88 90%

53 54%

50 51%

38 39%

25 26%

25 26%

22 22%

18 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause not drinking in dogs?: 98 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not drinking with similar medicines

Not drinking after Carprofen (Rimadyl) 270 reports · 0.6% of its reports
Not drinking after Deracoxib (Deramaxx) 31 reports · 0.3% of its reports
Not drinking after Meloxicam (Metacam) 65 reports · 0.8% of its reports
Not drinking after Firocoxib (Previcox) 44 reports · 0.5% of its reports

All reported side effects of Grapiprant in dogs · Medicines most reported with not drinking