Lameness after Grapiprant (Galliprant) in dogs

244 reports to the FDA describe lameness in dogs given Grapiprant. That is 2.8% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

244Reports
50%Marked serious
9.4%Recovered
12%Died or euthanised
30 daysTypical onset
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How soon it started

Same day
29 15%
1–2 days
18 9.2%
3–7 days
17 8.7%
1–4 weeks
37 19%
Over a month
95 48%

How the animals did

Recovered
20 8.2%
Recovered with lasting effects
3 1.2%
Still unwell when reported
130 53%
Died
9 3.7%
Euthanised
21 8.6%
Not known
61 25%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
17
4–7 years
38
8–11 years
91
12+ years
85

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause lameness in dogs?
244 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 30 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lameness with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with lameness