Skin redness after Fluralaner (Bravecto) in dogs

The FDA has received 519 reports of skin redness in dogs after Fluralaner. That is 0.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

519Reports

80%Marked serious

27%Recovered

5.4%Died or euthanised

1 daysTypical onset

How soon it started

Same day

130 35%

1–2 days

95 25%

3–7 days

48 13%

1–4 weeks

40 11%

Over a month

60 16%

How the animals did

Recovered

132 25%

Recovered with lasting effects

8 1.5%

Still unwell when reported

277 53%

Died

13 2.5%

Euthanised

15 2.9%

Not known

74 14%

Problems reported at the same time

192 37%

135 26%

126 24%

99 19%

92 18%

84 16%

Skin rash or irritation

73 14%

Hair loss

71 14%

Age of the animals

Under 1 year

1–3 years

149

4–7 years

165

8–11 years

110

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause skin redness in dogs?: 519 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin redness with similar medicines

Skin redness after Afoxolaner (NexGard) 1,053 reports · 1.8% of its reports
Skin redness after Sarolaner (Simparica) 119 reports · 0.7% of its reports
Skin redness after Lotilaner (Credelio) 110 reports · 1.1% of its reports
Skin redness after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 50 reports · 0.5% of its reports
Skin redness after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 45 reports · 1.5% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with skin redness