Cushings disease after Fluralaner (Bravecto) in dogs

26 reports to the FDA describe cushings disease in dogs given Fluralaner. That is 0.0% of all reports for this medicine, compared with 0.0% across reports for all dog medicines.

26Reports
100%Marked serious
62%Recovered
0.0%Died or euthanised
–Typical onset
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How the animals did

Recovered with lasting effects
16 62%
Still unwell when reported
7 27%
Not known
3 12%

Problems reported at the same time

Cutaneous calcinosis
4 15%
3 12%

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
0
8–11 years
12
12+ years
11

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause cushings disease in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Fluralaner in dogs · Medicines most reported with cushings disease