Fipronil side effects in dogs
1,411 reports sent to the FDA between 2010 and 2026 involve Fipronil in dogs. The most reported problems were vomiting, lethargy, itching. 26% were marked serious, and where it was recorded, signs eased after stopping the medicine in 0% of cases.
1,411Reports
26%Marked serious
0.1%Only medicine involved
41%Recovered
3.8%Died or euthanised
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About this medicine
Fipronil kills fleas and ticks (spot-on).
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (912 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Labrador Retriever 99 reports
- Yorkshire Terrier 47 reports
- Shih Tzu 47 reports
- German Shepherd Dog 44 reports
- Golden Retriever 37 reports
- Chihuahua 29 reports
- Australian Shepherd Dog 21 reports
- Cocker American Spaniel 19 reports
- German Pomeranian Spitz 17 reports
- Boston Terrier 17 reports
Other flea and tick treatments for dogs
Spinosad (Comfortis)57,095 reports · 7.7% seriousLufenuron + Milbemycin Oxime (Sentinel)26,051 reports · 24% seriousImidacloprid + Moxidectin (Advantage Multi)13,117 reports · 57% seriousNitenpyram (Capstar)10,782 reports · 10.0% seriousLufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum)9,966 reports · 40% seriousFipronil + S-methoprene (Frontline Plus)2,954 reports · 49% seriousFlumethrin + Imidacloprid (Seresto)2,273 reports · 25% seriousImidacloprid1,908 reports · 11% serious