Lethargy after Fipronil in dogs

The FDA has received 185 reports of lethargy in dogs after Fipronil. That is 13% of all reports for this medicine, compared with 11% across reports for all dog medicines.

185Reports
42%Marked serious
50%Recovered
9.2%Died or euthanised
31 daysTypical onset
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How soon it started

Same day
23 18%
1–2 days
13 9.9%
3–7 days
7 5.3%
1–4 weeks
22 17%
Over a month
66 50%

How the animals did

Recovered
75 41%
Recovered with lasting effects
17 9.2%
Still unwell when reported
33 18%
Died
7 3.8%
Euthanised
10 5.4%
Not known
43 23%

Problems reported at the same time

75 41%
39 21%
21 11%
18 9.7%
Dehydration
16 8.6%

Age of the animals

Under 1 year
20
1–3 years
47
4–7 years
51
8–11 years
39
12+ years
26

About this medicine

Fipronil kills fleas and ticks (spot-on).

Questions owners ask

Can Fipronil cause lethargy in dogs?
185 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 31 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Fipronil in dogs · Medicines most reported with lethargy