Pacing after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

The FDA has received 75 reports of pacing in dogs after Febantel + Praziquantel + Pyrantel. That is 1.1% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

75Reports
25%Marked serious
45%Recovered
1.3%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
37 65%
1–2 days
9 16%
3–7 days
3 5.3%
1–4 weeks
5 8.8%
Over a month
3 5.3%

How the animals did

Recovered
34 45%
Still unwell when reported
9 12%
Died
1 1.3%
Not known
31 41%

Problems reported at the same time

Age of the animals

Under 1 year
34
1–3 years
21
4–7 years
10
8–11 years
4
12+ years
2

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause pacing in dogs?
75 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pacing with similar medicines

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with pacing