Hyperphosphataemia after Famotidine in dogs

The FDA has received 125 reports of hyperphosphataemia in dogs after Famotidine. That is 4.7% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

125Reports
89%Marked serious
7.2%Recovered
62%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
17 17%
1–2 days
26 25%
3–7 days
18 18%
1–4 weeks
22 22%
Over a month
19 19%

How the animals did

Recovered
7 5.6%
Recovered with lasting effects
2 1.6%
Still unwell when reported
31 25%
Died
28 22%
Euthanised
50 40%
Not known
7 5.6%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
21
4–7 years
27
8–11 years
37
12+ years
25

About this medicine

Type: medicine.

Questions owners ask

Can Famotidine cause hyperphosphataemia in dogs?
125 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Famotidine in dogs · Medicines most reported with hyperphosphataemia