Eprinomectin side effects in dogs

105 reports sent to the FDA between 2000 and 2025 involve Eprinomectin in dogs. The most reported problems were eye or vision problems, accidental exposure, wobbliness (ataxia). 27% were marked serious.

105Reports
27%Marked serious
99%Only medicine involved
7.6%Recovered
7.6%Died or euthanised
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About this medicine

Eprinomectin controls worms and prevents heartworm.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Most reported side effects

20 19%
Drooling
19 18%
Lethargy
15 14%
Tremors
9 8.6%
Disorientation
8 7.6%
Loss of appetite
6 5.7%
Restlessness or agitation
6 5.7%
Dilated pupils
6 5.7%
Recumbency
5 4.8%
Loss of consciousness
4 3.8%
Abnormal pupil light reflex
4 3.8%
Fixed pupil
3 2.9%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

How soon problems started

Same day
16 62%
1–2 days
10 38%
3–7 days
0 0.0%
1–4 weeks
0 0.0%
Over a month
0 0.0%

Time from the first dose to the first sign, where both dates were reported (26 reports).

How the animals did

Recovered
8 7.6%
Still unwell when reported
6 5.7%
Died
8 7.6%
Not known
83 79%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other macrocyclic lactone (heartworm and parasite prevention)s for dogs