Wobbliness (ataxia) after Eprinomectin in dogs

30 reports to the FDA describe wobbliness (ataxia) in dogs given Eprinomectin. That is 29% of all reports for this medicine, compared with 2.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

30Reports

23%Marked serious

3.3%Recovered

10%Died or euthanised

–Typical onset

How the animals did

Recovered

1 3.3%

Died

3 10%

Not known

26 87%

Problems reported at the same time

Eye or vision problems

23 77%

Accidental exposure

15 50%

Vomiting

7 23%

Drooling

6 20%

Lethargy

5 17%

Death

3 10%

Loss of appetite

3 10%

Disorientation

2 6.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Eprinomectin controls worms and prevents heartworm.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Eprinomectin cause wobbliness (ataxia) in dogs?: 30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Wobbliness (ataxia) with similar medicines

Wobbliness (ataxia) after Ivermectin + Pyrantel (Heartgard Plus) 1,346 reports · 0.9% of its reports
Wobbliness (ataxia) after Milbemycin Oxime + Spinosad (Trifexis) 2,821 reports · 2.2% of its reports
Wobbliness (ataxia) after Moxidectin (ProHeart 6) 1,147 reports · 2.3% of its reports
Wobbliness (ataxia) after Milbemycin Oxime + Praziquantel (Interceptor Plus) 533 reports · 1.7% of its reports
Wobbliness (ataxia) after Milbemycin Oxime (Interceptor) 712 reports · 2.4% of its reports
Wobbliness (ataxia) after Selamectin (Revolution) 622 reports · 2.1% of its reports
Wobbliness (ataxia) after Ivermectin (Heartgard) 1,237 reports · 10% of its reports
Wobbliness (ataxia) after Ivermectin + Praziquantel + Pyrantel (Iverhart Max) 119 reports · 1.4% of its reports
Wobbliness (ataxia) after Moxidectin + Pyrantel + Sarolaner (Simparica Trio) 24 reports · 2.1% of its reports
Wobbliness (ataxia) after Ivermectin + Praziquantel 81 reports · 40% of its reports

All reported side effects of Eprinomectin in dogs · Medicines most reported with wobbliness (ataxia)