Frequent urination after Doxycycline in dogs

20 reports to the FDA describe frequent urination in dogs given Doxycycline. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports

70%Marked serious

10%Recovered

35%Died or euthanised

22 daysTypical onset

How soon it started

Same day

1 6.3%

1–2 days

1 6.3%

3–7 days

1 6.3%

1–4 weeks

7 44%

Over a month

6 38%

How the animals did

Recovered

1 5.0%

Recovered with lasting effects

1 5.0%

Still unwell when reported

9 45%

Died

1 5.0%

Euthanised

6 30%

Not known

2 10%

Problems reported at the same time

10 50%

9 45%

9 45%

7 35%

Didn't work as expected

7 35%

Kidney problems

7 35%

Neutrophilia

7 35%

Haematuria

6 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause frequent urination in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 22 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Frequent urination with similar medicines

Frequent urination after Amoxicillin + Clavulanate (Clavamox) 34 reports · 0.6% of its reports
Frequent urination after Enrofloxacin (Baytril) 23 reports · 0.6% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with frequent urination