Haematuria after Doxycycline in dogs

The FDA has received 47 reports of haematuria in dogs after Doxycycline. That is 1.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

47Reports

74%Marked serious

6.4%Recovered

40%Died or euthanised

27 daysTypical onset

How soon it started

Same day

7 19%

1–2 days

0 0.0%

3–7 days

1 2.7%

1–4 weeks

14 38%

Over a month

15 41%

How the animals did

Recovered

3 6.4%

Still unwell when reported

19 40%

Died

5 11%

Euthanised

14 30%

Not known

6 13%

Problems reported at the same time

28 60%

25 53%

25 53%

24 51%

20 43%

20 43%

19 40%

16 34%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause haematuria in dogs?: 47 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Haematuria with similar medicines

Haematuria after Amoxicillin + Clavulanate (Clavamox) 134 reports · 2.5% of its reports
Haematuria after Cefovecin (Convenia) 42 reports · 1.1% of its reports
Haematuria after Enrofloxacin (Baytril) 62 reports · 1.6% of its reports
Haematuria after Metronidazole 30 reports · 1.0% of its reports
Haematuria after Amoxicillin 42 reports · 3.1% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with haematuria