Haematuria after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 134 reports of haematuria in dogs after Amoxicillin + Clavulanate. That is 2.5% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

134Reports
43%Marked serious
4.5%Recovered
22%Died or euthanised
28 daysTypical onset
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How soon it started

Same day
4 6.0%
1–2 days
8 12%
3–7 days
4 6.0%
1–4 weeks
22 33%
Over a month
29 43%

How the animals did

Recovered
5 3.7%
Recovered with lasting effects
1 0.7%
Still unwell when reported
47 35%
Died
19 14%
Euthanised
11 8.2%
Not known
51 38%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
12
4–7 years
40
8–11 years
47
12+ years
23

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause haematuria in dogs?
134 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 28 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Haematuria with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with haematuria