Elevated temperature after Doxycycline in dogs

21 reports to the FDA describe elevated temperature in dogs given Doxycycline. That is 0.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

71%Marked serious

14%Recovered

9.5%Died or euthanised

7 daysTypical onset

How soon it started

Same day

3 19%

1–2 days

2 13%

3–7 days

4 25%

1–4 weeks

4 25%

Over a month

3 19%

How the animals did

Recovered

3 14%

Still unwell when reported

11 52%

Died

1 4.8%

Euthanised

1 4.8%

Not known

5 24%

Problems reported at the same time

13 62%

12 57%

7 33%

6 29%

5 24%

5 24%

5 24%

5 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause elevated temperature in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated temperature with similar medicines

Elevated temperature after Amoxicillin + Clavulanate (Clavamox) 37 reports · 0.7% of its reports
Elevated temperature after Enrofloxacin (Baytril) 27 reports · 0.7% of its reports
Elevated temperature after Metronidazole 33 reports · 1.1% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with elevated temperature