Pale mucous membrane after Diphenhydramine in dogs

The FDA has received 293 reports of pale mucous membrane in dogs after Diphenhydramine. That is 6.2% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Type: medicine.

Questions owners ask

Can Diphenhydramine cause pale mucous membrane in dogs?

293 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within the same day of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pale mucous membrane with similar medicines

• Pale mucous membrane after Melarsomine (Immiticide) 454 reports · 2.0% of its reports
• Pale mucous membrane after Polysulfated Glycosaminoglycan 80 reports · 1.5% of its reports
• Pale mucous membrane after Butorphanol 146 reports · 3.3% of its reports
• Pale mucous membrane after Cefpodoxime 78 reports · 1.9% of its reports
• Pale mucous membrane after Tramadol 107 reports · 2.8% of its reports
• Pale mucous membrane after Florfenicol + Mometasone + Terbinafine 35 reports · 1.0% of its reports
• Pale mucous membrane after Desoxycorticosterone Pivalate 30 reports · 0.9% of its reports
• Pale mucous membrane after Propofol 114 reports · 3.7% of its reports
• Pale mucous membrane after Isoflurane 99 reports · 3.6% of its reports
• Pale mucous membrane after Cephalexin 43 reports · 1.6% of its reports

All reported side effects of Diphenhydramine in dogs · Medicines most reported with pale mucous membrane