Leucopenia after Diphenhydramine in dogs
The FDA has received 68 reports of leucopenia in dogs after Diphenhydramine. That is 1.4% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.
68Reports
59%Marked serious
12%Recovered
28%Died or euthanised
2 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Type: medicine.
Questions owners ask
- Can Diphenhydramine cause leucopenia in dogs?
- 68 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 2 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Leucopenia with similar medicines
- Leucopenia after Melarsomine (Immiticide) 101 reports · 0.4% of its reports
- Leucopenia after Polysulfated Glycosaminoglycan 34 reports · 0.6% of its reports
- Leucopenia after Butorphanol 39 reports · 0.9% of its reports
- Leucopenia after Cefpodoxime 60 reports · 1.5% of its reports
- Leucopenia after Tramadol 53 reports · 1.4% of its reports
- Leucopenia after Propofol 33 reports · 1.1% of its reports
- Leucopenia after Isoflurane 29 reports · 1.0% of its reports
- Leucopenia after Cephalexin 27 reports · 1.0% of its reports
- Leucopenia after Atipamezole 22 reports · 0.8% of its reports
- Leucopenia after Famotidine 75 reports · 2.8% of its reports
All reported side effects of Diphenhydramine in dogs · Medicines most reported with leucopenia