Increased respiratory rate after Diphenhydramine in dogs
The FDA has received 42 reports of increased respiratory rate in dogs after Diphenhydramine. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
42Reports
83%Marked serious
21%Recovered
33%Died or euthanised
Same dayTypical onset
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Type: medicine.
Questions owners ask
- Can Diphenhydramine cause increased respiratory rate in dogs?
- 42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Increased respiratory rate with similar medicines
- Increased respiratory rate after Melarsomine (Immiticide) 81 reports · 0.4% of its reports
- Increased respiratory rate after Polysulfated Glycosaminoglycan 21 reports · 0.4% of its reports
- Increased respiratory rate after Butorphanol 26 reports · 0.6% of its reports
- Increased respiratory rate after Tramadol 39 reports · 1.0% of its reports
- Increased respiratory rate after Isoflurane 20 reports · 0.7% of its reports
- Increased respiratory rate after Famotidine 25 reports · 0.9% of its reports
- Increased respiratory rate after Furosemide 33 reports · 2.2% of its reports
- Increased respiratory rate after Ampicillin 25 reports · 2.6% of its reports
All reported side effects of Diphenhydramine in dogs · Medicines most reported with increased respiratory rate
