Hypotension after Dexmedetomidine (Dexdomitor) in dogs

94 reports to the FDA describe hypotension in dogs given Dexmedetomidine. That is 1.7% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

94Reports

62%Marked serious

44%Recovered

34%Died or euthanised

Same dayTypical onset

How soon it started

Same day

58 79%

1–2 days

5 6.8%

3–7 days

4 5.5%

1–4 weeks

1 1.4%

Over a month

5 6.8%

How the animals did

Recovered

41 44%

Still unwell when reported

13 14%

Died

20 21%

Euthanised

12 13%

Not known

8 8.5%

Problems reported at the same time

39 41%

30 32%

22 23%

17 18%

16 17%

14 15%

13 14%

Didn't work as expected

13 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause hypotension in dogs?: 94 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypotension with similar medicines

Hypotension after Buprenorphine 39 reports · 2.5% of its reports

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with hypotension