Hypotension after Buprenorphine in dogs

39 reports to the FDA describe hypotension in dogs given Buprenorphine. That is 2.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

39Reports

82%Marked serious

31%Recovered

54%Died or euthanised

2 daysTypical onset

How soon it started

Same day

14 41%

1–2 days

4 12%

3–7 days

3 8.8%

1–4 weeks

7 21%

Over a month

6 18%

How the animals did

Recovered

12 31%

Still unwell when reported

4 10%

Died

4 10%

Euthanised

17 44%

Not known

2 5.1%

Problems reported at the same time

21 54%

19 49%

18 46%

15 38%

15 38%

13 33%

13 33%

Abnormal radiograph finding

12 31%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause hypotension in dogs?: 39 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypotension with similar medicines

Hypotension after Dexmedetomidine (Dexdomitor) 94 reports · 1.7% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with hypotension