Hyperexcitation after Dexmedetomidine (Dexdomitor) in dogs

25 reports to the FDA describe hyperexcitation in dogs given Dexmedetomidine. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports
12%Marked serious
32%Recovered
20%Died or euthanised
–Typical onset
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How the animals did

Recovered
8 32%
Died
4 16%
Euthanised
1 4.0%
Not known
12 48%

Problems reported at the same time

4 16%
Paddling
4 16%
Premature anaesthesia recovery
3 12%

Age of the animals

Under 1 year
1
1–3 years
7
4–7 years
4
8–11 years
6
12+ years
0

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause hyperexcitation in dogs?
25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Dexmedetomidine in dogs · Medicines most reported with hyperexcitation