Behaviour change after Dexamethasone in dogs

The FDA has received 139 reports of behaviour change in dogs after Dexamethasone. That is 5.1% of all reports for this medicine, compared with 2.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

139Reports
68%Marked serious
19%Recovered
22%Died or euthanised
1 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
57 49%
1–2 days
20 17%
3–7 days
8 6.8%
1–4 weeks
13 11%
Over a month
19 16%

How the animals did

Recovered
27 19%
Still unwell when reported
58 42%
Died
12 8.6%
Euthanised
18 13%
Not known
24 17%

Problems reported at the same time

Age of the animals

Under 1 year
11
1–3 years
53
4–7 years
42
8–11 years
21
12+ years
12

About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Dexamethasone cause behaviour change in dogs?
139 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Dexamethasone in dogs · Medicines most reported with behaviour change