Hyponatremia after Deracoxib (Deramaxx) in dogs

113 reports to the FDA describe hyponatremia in dogs given Deracoxib. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

113Reports
17%Marked serious
2.7%Recovered
50%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
0 0.0%
1–2 days
2 18%
3–7 days
3 27%
1–4 weeks
3 27%
Over a month
3 27%

How the animals did

Recovered
3 2.7%
Still unwell when reported
6 5.3%
Died
46 41%
Euthanised
10 8.8%
Not known
48 42%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
20
4–7 years
31
8–11 years
43
12+ years
16

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause hyponatremia in dogs?
113 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyponatremia with similar medicines

All reported side effects of Deracoxib in dogs · Medicines most reported with hyponatremia