Hyponatremia after Meloxicam (Metacam) in dogs

The FDA has received 78 reports of hyponatremia in dogs after Meloxicam. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports
69%Marked serious
14%Recovered
27%Died or euthanised
2 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
14 29%
1–2 days
12 25%
3–7 days
14 29%
1–4 weeks
7 15%
Over a month
1 2.1%

How the animals did

Recovered
9 12%
Recovered with lasting effects
2 2.6%
Still unwell when reported
14 18%
Died
9 12%
Euthanised
12 15%
Not known
32 41%

Problems reported at the same time

Age of the animals

Under 1 year
19
1–3 years
21
4–7 years
13
8–11 years
18
12+ years
6

About this medicine

Meloxicam relieves pain and inflammation.

Products with this ingredient include Metacam. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Meloxicam cause hyponatremia in dogs?
78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyponatremia with similar medicines

All reported side effects of Meloxicam in dogs · Medicines most reported with hyponatremia