Urine abnormalities after Cyclosporine (Atopica) in dogs

31 reports to the FDA describe urine abnormalities in dogs given Cyclosporine. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

31Reports

68%Marked serious

19%Recovered

23%Died or euthanised

3 daysTypical onset

How soon it started

Same day

1 5.9%

1–2 days

4 24%

3–7 days

4 24%

1–4 weeks

4 24%

Over a month

4 24%

How the animals did

Recovered

5 16%

Recovered with lasting effects

1 3.2%

Still unwell when reported

14 45%

Died

1 3.2%

Euthanised

6 19%

Not known

4 13%

Problems reported at the same time

14 45%

13 42%

13 42%

12 39%

12 39%

11 35%

Urinary tract infection

9 29%

Excessive thirst

8 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause urine abnormalities in dogs?: 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urine abnormalities with similar medicines

Urine abnormalities after Oclacitinib (Apoquel) 228 reports · 0.8% of its reports
Urine abnormalities after Ilunocitinib (Zenrelia) 31 reports · 1.4% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with urine abnormalities