Malaise after Cyclosporine (Atopica) in dogs

67 reports to the FDA describe malaise in dogs given Cyclosporine. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

67Reports

58%Marked serious

21%Recovered

27%Died or euthanised

15 daysTypical onset

How soon it started

Same day

10 27%

1–2 days

2 5.4%

3–7 days

3 8.1%

1–4 weeks

7 19%

Over a month

15 41%

How the animals did

Recovered

13 19%

Recovered with lasting effects

1 1.5%

Still unwell when reported

16 24%

Died

9 13%

Euthanised

9 13%

Not known

19 28%

Problems reported at the same time

27 40%

24 36%

20 30%

18 27%

15 22%

14 21%

13 19%

10 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause malaise in dogs?: 67 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 15 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

Malaise after Oclacitinib (Apoquel) 131 reports · 0.5% of its reports
Malaise after Ilunocitinib (Zenrelia) 22 reports · 1.0% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with malaise