Excessive urination after Cyclosporine (Atopica) in dogs

The FDA has received 425 reports of excessive urination in dogs after Cyclosporine. That is 2.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

425Reports
29%Marked serious
8.5%Recovered
8.0%Died or euthanised
25 daysTypical onset
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How soon it started

Same day
15 16%
1–2 days
9 9.7%
3–7 days
9 9.7%
1–4 weeks
18 19%
Over a month
42 45%

How the animals did

Recovered
24 5.6%
Recovered with lasting effects
12 2.8%
Still unwell when reported
73 17%
Died
23 5.4%
Euthanised
11 2.6%
Not known
282 66%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
49
4–7 years
120
8–11 years
164
12+ years
83

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause excessive urination in dogs?
425 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 25 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

All reported side effects of Cyclosporine in dogs · Medicines most reported with excessive urination