Hyperglycaemia after Cyclosporine (Atopica) in dogs

211 reports to the FDA describe hyperglycaemia in dogs given Cyclosporine. That is 1.4% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

211Reports

34%Marked serious

11%Recovered

13%Died or euthanised

39 daysTypical onset

How soon it started

Same day

4 9.3%

1–2 days

1 2.3%

3–7 days

7 16%

1–4 weeks

9 21%

Over a month

22 51%

How the animals did

Recovered

7 3.3%

Recovered with lasting effects

16 7.6%

Still unwell when reported

35 17%

Died

16 7.6%

Euthanised

11 5.2%

Not known

126 60%

Problems reported at the same time

97 46%

81 38%

80 38%

78 37%

76 36%

70 33%

61 29%

59 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause hyperglycaemia in dogs?: 211 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 39 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperglycaemia with similar medicines

Hyperglycaemia after Oclacitinib (Apoquel) 185 reports · 0.6% of its reports
Hyperglycaemia after Ilunocitinib (Zenrelia) 33 reports · 1.5% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with hyperglycaemia