Elevated cholesterol (total) after Cyclosporine (Atopica) in dogs

105 reports to the FDA describe elevated cholesterol (total) in dogs given Cyclosporine. That is 0.7% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

105Reports
24%Marked serious
3.8%Recovered
9.5%Died or euthanised
45 daysTypical onset
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How soon it started

Same day
3 16%
1–2 days
0 0.0%
3–7 days
3 16%
1–4 weeks
3 16%
Over a month
10 53%

How the animals did

Recovered with lasting effects
4 3.8%
Still unwell when reported
21 20%
Died
7 6.7%
Euthanised
3 2.9%
Not known
70 67%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
8
4–7 years
25
8–11 years
53
12+ years
17

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause elevated cholesterol (total) in dogs?
105 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 45 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

All reported side effects of Cyclosporine in dogs · Medicines most reported with elevated cholesterol (total)