Lethargy after Capromorelin (Entyce) in dogs

361 reports to the FDA describe lethargy in dogs given Capromorelin. That is 24% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

361Reports
65%Marked serious
22%Recovered
33%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
116 37%
1–2 days
46 15%
3–7 days
43 14%
1–4 weeks
43 14%
Over a month
66 21%

How the animals did

Recovered
79 22%
Recovered with lasting effects
2 0.6%
Still unwell when reported
85 24%
Died
42 12%
Euthanised
77 21%
Not known
76 21%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
36
4–7 years
67
8–11 years
97
12+ years
126

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause lethargy in dogs?
361 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Capromorelin in dogs · Medicines most reported with lethargy