Kidney problems after Capromorelin (Entyce) in dogs

The FDA has received 194 reports of kidney problems in dogs after Capromorelin. That is 13% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

194Reports

88%Marked serious

4.1%Recovered

54%Died or euthanised

10 daysTypical onset

How soon it started

Same day

36 22%

1–2 days

22 14%

3–7 days

16 9.9%

1–4 weeks

33 20%

Over a month

54 34%

How the animals did

Recovered

8 4.1%

Still unwell when reported

48 25%

Died

29 15%

Euthanised

76 39%

Not known

33 17%

Problems reported at the same time

120 62%

104 54%

102 53%

92 47%

72 37%

59 30%

54 28%

51 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause kidney problems in dogs?: 194 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Maropitant (Cerenia) 1,334 reports · 11% of its reports
Kidney problems after Mirtazapine (Mirataz) 69 reports · 24% of its reports

All reported side effects of Capromorelin in dogs · Medicines most reported with kidney problems