Death after Capromorelin (Entyce) in dogs

The FDA has received 358 reports of death in dogs after Capromorelin. That is 24% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

358Reports

100%Marked serious

0.3%Recovered

99%Died or euthanised

7 daysTypical onset

How soon it started

Same day

67 22%

1–2 days

47 16%

3–7 days

39 13%

1–4 weeks

56 19%

Over a month

90 30%

How the animals did

Recovered

1 0.3%

Died

146 41%

Euthanised

210 59%

Not known

1 0.3%

Problems reported at the same time

149 42%

117 33%

104 29%

101 28%

99 28%

Didn't work as expected

66 18%

Blood problems

66 18%

Breathing problems

58 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

108

12+ years

119

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause death in dogs?: 358 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Maropitant (Cerenia) 2,625 reports · 22% of its reports
Death after Mirtazapine (Mirataz) 102 reports · 35% of its reports

All reported side effects of Capromorelin in dogs · Medicines most reported with death