Didn't work as expected after Capromorelin (Entyce) in dogs

The FDA has received 357 reports of didn't work as expected in dogs after Capromorelin. That is 24% of all reports for this medicine, compared with 13% across reports for all dog medicines, so it is reported unusually often with this medicine.

357Reports
36%Marked serious
5.9%Recovered
19%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
109 34%
1–2 days
47 14%
3–7 days
38 12%
1–4 weeks
41 13%
Over a month
90 28%

How the animals did

Recovered
21 5.9%
Still unwell when reported
37 10%
Died
27 7.6%
Euthanised
40 11%
Not known
232 65%

Problems reported at the same time

Age of the animals

Under 1 year
35
1–3 years
25
4–7 years
46
8–11 years
59
12+ years
136

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause didn't work as expected in dogs?
357 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Capromorelin in dogs · Medicines most reported with didn't work as expected