Kidney problems after Mirtazapine (Mirataz) in dogs

69 reports to the FDA describe kidney problems in dogs given Mirtazapine. That is 24% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

69Reports

87%Marked serious

4.3%Recovered

54%Died or euthanised

11 daysTypical onset

How soon it started

Same day

6 11%

1–2 days

10 18%

3–7 days

7 13%

1–4 weeks

17 30%

Over a month

16 29%

How the animals did

Recovered

3 4.3%

Still unwell when reported

25 36%

Died

7 10%

Euthanised

30 43%

Not known

4 5.8%

Problems reported at the same time

56 81%

37 54%

37 54%

33 48%

30 43%

22 32%

22 32%

21 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Mirtazapine stimulates appetite (cats: ointment applied to the ear).

Products with this ingredient include Mirataz. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Mirtazapine cause kidney problems in dogs?: 69 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Maropitant (Cerenia) 1,334 reports · 11% of its reports
Kidney problems after Capromorelin (Entyce) 194 reports · 13% of its reports

All reported side effects of Mirtazapine in dogs · Medicines most reported with kidney problems