Loss of appetite after Mirtazapine (Mirataz) in dogs

The FDA has received 156 reports of loss of appetite in dogs after Mirtazapine. That is 54% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

156Reports
78%Marked serious
11%Recovered
41%Died or euthanised
11 daysTypical onset
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How soon it started

Same day
19 15%
1–2 days
17 13%
3–7 days
17 13%
1–4 weeks
39 30%
Over a month
36 28%

How the animals did

Recovered
16 10%
Recovered with lasting effects
1 0.6%
Still unwell when reported
61 39%
Died
12 7.7%
Euthanised
52 33%
Not known
14 9.0%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
9
4–7 years
42
8–11 years
53
12+ years
49

About this medicine

Mirtazapine stimulates appetite (cats: ointment applied to the ear).

Products with this ingredient include Mirataz. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Mirtazapine cause loss of appetite in dogs?
156 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 11 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Mirtazapine in dogs · Medicines most reported with loss of appetite