Lethargy after Maropitant (Cerenia) in dogs

The FDA has received 3,148 reports of lethargy in dogs after Maropitant. That is 26% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

3,148Reports

65%Marked serious

15%Recovered

30%Died or euthanised

1 daysTypical onset

How soon it started

Same day

975 37%

1–2 days

543 20%

3–7 days

368 14%

1–4 weeks

378 14%

Over a month

401 15%

How the animals did

Recovered

452 14%

Recovered with lasting effects

7 0.2%

Still unwell when reported

1,258 40%

Died

424 13%

Euthanised

510 16%

Not known

497 16%

Problems reported at the same time

1,848 59%

1,735 55%

942 30%

923 29%

898 29%

607 19%

519 16%

478 15%

Age of the animals

Under 1 year

344

1–3 years

688

4–7 years

772

8–11 years

778

12+ years

517

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause lethargy in dogs?: 3,148 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

Lethargy after Capromorelin (Entyce) 361 reports · 24% of its reports
Lethargy after Mirtazapine (Mirataz) 95 reports · 33% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with lethargy