Anxiety after Capromorelin (Entyce) in dogs

The FDA has received 20 reports of anxiety in dogs after Capromorelin. That is 1.3% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports

95%Marked serious

5.0%Recovered

55%Died or euthanised

10 daysTypical onset

How soon it started

Same day

4 22%

1–2 days

4 22%

3–7 days

1 5.6%

1–4 weeks

5 28%

Over a month

4 22%

How the animals did

Recovered

1 5.0%

Still unwell when reported

2 10%

Died

3 15%

Euthanised

8 40%

Not known

6 30%

Problems reported at the same time

11 55%

9 45%

9 45%

8 40%

7 35%

7 35%

5 25%

5 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause anxiety in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Anxiety with similar medicines

Anxiety after Maropitant (Cerenia) 134 reports · 1.1% of its reports

All reported side effects of Capromorelin in dogs · Medicines most reported with anxiety