Anxiety after Maropitant (Cerenia) in dogs

The FDA has received 134 reports of anxiety in dogs after Maropitant. That is 1.1% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

134Reports

57%Marked serious

22%Recovered

17%Died or euthanised

1 daysTypical onset

How soon it started

Same day

49 41%

1–2 days

21 18%

3–7 days

12 10%

1–4 weeks

13 11%

Over a month

24 20%

How the animals did

Recovered

30 22%

Still unwell when reported

50 37%

Died

8 6.0%

Euthanised

15 11%

Not known

31 23%

Problems reported at the same time

59 44%

48 36%

36 27%

35 26%

33 25%

30 22%

28 21%

27 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause anxiety in dogs?: 134 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Anxiety with similar medicines

Anxiety after Capromorelin (Entyce) 20 reports · 1.3% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with anxiety