Benadryl side effects in dogs

241 reports sent to the FDA between 2012 and 2026 involve Benadryl in dogs. The most reported problems were vomiting, lethargy, loss of appetite. 80% were marked serious, and where it was recorded, signs eased after stopping the medicine in 0% of cases.

241Reports
80%Marked serious
0.0%Only medicine involved
16%Recovered
13%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

73 30%
55 23%
53 22%
40 17%
40 17%
20 8.3%
Skin rash or irritation
17 7.1%
Skin redness
17 7.1%
Fever
17 7.1%
Behaviour change
12 5.0%
Wobbliness (ataxia)
12 5.0%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't work as expected
19 7.9%
Didn't stop fleas
4 1.7%
Didn't prevent heartworm
2 0.8%
Didn't stop worms
1 0.4%

How soon problems started

Same day
98 46%
1–2 days
26 12%
3–7 days
28 13%
1–4 weeks
22 10%
Over a month
37 18%

Time from the first dose to the first sign, where both dates were reported (211 reports).

How the animals did

Recovered
39 16%
Still unwell when reported
144 60%
Died
16 6.6%
Euthanised
15 6.2%
Not known
27 11%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for dogs