Itching after Benadryl in dogs

40 reports to the FDA describe itching in dogs given Benadryl. That is 17% of all reports for this medicine, compared with 4.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports
80%Marked serious
15%Recovered
2.5%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
18 53%
1–2 days
4 12%
3–7 days
5 15%
1–4 weeks
3 8.8%
Over a month
4 12%

How the animals did

Recovered
6 15%
Still unwell when reported
26 65%
Died
1 2.5%
Not known
7 18%

Problems reported at the same time

11 28%
Skin rash or irritation
8 20%
Skin redness
7 18%

Age of the animals

Under 1 year
5
1–3 years
9
4–7 years
12
8–11 years
6
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can Benadryl cause itching in dogs?
40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Itching with similar medicines

All reported side effects of Benadryl in dogs · Medicines most reported with itching