Elevated symmetrical dimethylarginine (sdma) after Bedinvetmab (Librela) in dogs
The FDA has received 300 reports of elevated symmetrical dimethylarginine (sdma) in dogs after Bedinvetmab. That is 1.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
300Reports
69%Marked serious
5.0%Recovered
25%Died or euthanised
19 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).
Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Bedinvetmab cause elevated symmetrical dimethylarginine (sdma) in dogs?
- 300 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 19 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Elevated symmetrical dimethylarginine (sdma) with similar medicines
- Elevated symmetrical dimethylarginine (sdma) after Lokivetmab (Cytopoint) 42 reports · 0.6% of its reports
All reported side effects of Bedinvetmab in dogs · Medicines most reported with elevated symmetrical dimethylarginine (sdma)