Proteinuria after Bedinvetmab (Librela) in dogs

415 reports to the FDA describe proteinuria in dogs given Bedinvetmab. That is 2.1% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

415Reports
68%Marked serious
3.4%Recovered
16%Died or euthanised
19 daysTypical onset
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How soon it started

Same day
39 11%
1–2 days
46 13%
3–7 days
45 12%
1–4 weeks
93 26%
Over a month
139 38%

How the animals did

Recovered
13 3.1%
Recovered with lasting effects
1 0.2%
Still unwell when reported
301 73%
Died
10 2.4%
Euthanised
56 13%
Not known
34 8.2%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
33
8–11 years
148
12+ years
228

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause proteinuria in dogs?
415 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 19 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

All reported side effects of Bedinvetmab in dogs · Medicines most reported with proteinuria