Elevated amylase after Amoxicillin in dogs

25 reports to the FDA describe elevated amylase in dogs given Amoxicillin. That is 1.9% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports

80%Marked serious

0.0%Recovered

36%Died or euthanised

7 daysTypical onset

How soon it started

Same day

4 27%

1–2 days

2 13%

3–7 days

4 27%

1–4 weeks

3 20%

Over a month

2 13%

How the animals did

Still unwell when reported

8 32%

Died

1 4.0%

Euthanised

8 32%

Not known

8 32%

Problems reported at the same time

19 76%

15 60%

14 56%

13 52%

13 52%

9 36%

9 36%

9 36%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause elevated amylase in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated amylase with similar medicines

Elevated amylase after Amoxicillin + Clavulanate (Clavamox) 73 reports · 1.4% of its reports
Elevated amylase after Doxycycline 43 reports · 1.1% of its reports
Elevated amylase after Cefovecin (Convenia) 37 reports · 1.0% of its reports
Elevated amylase after Enrofloxacin (Baytril) 55 reports · 1.5% of its reports
Elevated amylase after Metronidazole 58 reports · 1.9% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with elevated amylase